Abstract:An open pit mine is composed of two adjacent south and north open pits. The lowest mining level of the north open pit is -350m, and the south open pit is -50m, and the south open pit is planned to be closed after one year. In order to achieve the ecological restoration of the south open pit, it is planned to carry out the tailings cementation filling after the south open pit is closed. In order to ensure that the filling of the south open pit will not affect the normal and safe production of the north open pit, it is necessary to analyze the stability of the slope during the filling treatment of the open pit. Geo-Studio software is used to analyze the stability of the slope before and after the filling of the south open pit, and different working conditions such as the thickness of the filling revetment, the stacking height, groundwater, and seismic load conditions are considered. The research results can provide a basis for the filling treatment of the south open pit and the safety production of the north open pit.