Abstract:In a fluorite mine in Xinjiang, the main content is fluorite and calcite (32.90% and 53.63%, respectively), followed by quartz (7.43%). Some of the fluorite minerals in the ore have coarse grain size, and some of the fluorite forms veins and vein-like structure. At the same time, some fluorite metasomatism other minerals, which is difficult to dissociate. Beneficiation test research was carried out according to the ore properties. The test showed that when the grinding fineness of -0.074mm was 70%, the flotation process of “one coarse-six concentrate-one sweep” was adopted, acidized sodium silicate and AB-123C were used as inhibitors, the dosage of the two inhibitors were 600g/t and 300g/t, and AB-CD was used as collector, the dosage of which was 450g/t. A fluorite concentrate with a concentrate rate of 26.69%, a CaF2 grade of 97.21% (FC-97A quality), a CaF2 recovery of 83.13% and a CaF2 grade of 0.55% was obtained.