Abstract:As the mining of mineral resources gradually goes deep, the problem of high geostress will be encountered. The exploration of stope structure under high stress environment is the key to large-scale and high-efficiency mining. With Sishanling Iron Ore Mine as the research object, this paper will carry out the research on the stope structure of large-diameter deep-hole open stope with subsequent filling, simulate and analyze the traditional strip stope and square stope. The research shows that square stope layout is more favorable to stress distribution and engineering stability than strip stope layout. Therefore, it is recommended that the Sishanling Iron Ore Mine adopt 40m × 40m square stope for deep shaft mining, which can also provide reference for large-scale mining of the similar deep and thick mines.