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As a deep denitrification wastewater treatment technology, denitrification filter integrates denitrification and filtration, and can simultaneously remove suspended solids and total nitrogen in wastewater. It has been successfully applied in the advanced treatment of wastewater treatment plant. This article discusses the research progress of denitrification filters and introduces the process design of of denitrification filters in advanced treatment of wastewater treatment plant through engineering examples, including design points, design calculations and system design. The operating results show using DeniforV deep denitrification V-type filter and sodium acetate as a supplementary carbon source, the average removal rate of TN in the filter reaches 48.5%, and the effluent TN is less than 15mg/L.This article systematically summarizes the influencing factors and design points of denitrification filters, providing a reference for the design of advanced wastewater treatment.